Pioneers of Hope – Spring 2017

At Monroe Carell Jr. Children’s Hospital at Vanderbilt our work extends beyond patient exam rooms. We are also searching for discoveries to offer better treatments, and, hopefully, find cures for pediatric patients. The profiles here represent only a sampling of the tireless work performed daily to make Children’s Hospital a place of unwavering hope. In each issue, we also include a profile to highlight our longstanding partnership with our community pediatricians who help ensure all children receive the best care each and every day.

 

Robert Naftel, M.D., grew up witnessing the intense dedication, passion and life-changing moments that physicians experience. Yet, it wasn’t until college that he realized it was his calling.

“Many of my family members were various types of physicians and I was inspired by the way that I saw them affect others’ lives, each in their own way,” said Naftel, an assistant professor of Neurological Surgery at Vanderbilt University Medical Center (VUMC). “I did not go to college intending to be a physician, but I found that most of my interests revolved around service and science.”

The Birmingham, Alabama, native attended Washington and Lee University in Lexington, Virginia, inspired by a high school teacher to major in Chemistry. He ran cross country, served as president of the student body and was head adjudicator of the honor system.

Those leadership roles prepared him for future challenges, and his volunteer work also fostered in him a servant’s heart.

“When I volunteered in the local hospital, it felt like it was where I belonged,” Naftel said. “I wanted to be a part of the team that helped patients get through tough times in their lives.”

After completing a Bachelor of Science in Chemistry in 2002, Naftel moved home and enrolled at the University of Alabama (UA) School of Medicine. He was drawn to neurosurgery as a specialty and completed his residency training in neurosurgery at UA of Birmingham in 2012.

“When I was halfway through my six-year residency in neurosurgery, I was again drawn back to working with children and decided to specialize in pediatric neurosurgery,” Naftel said. “I enjoyed working with families and found the work to be meaningful, challenging and fulfilling.”

He completed a fellowship in pediatric neurosurgery in Pittsburgh. In August 2013, Naftel began his work at VUMC specializing in pediatric neurosurgery.

“Vanderbilt offered everything that I was looking for. There was a great opportunity and need in pediatric neurosurgery. It was clear that I was coming to a very supportive medical center. It was fertile ground for curious minds,” Naftel said. “I knew that I would have two amazing bosses—Reid Thompson, M.D., and Jay Wellons, M.D.—and I could trust them to foster my growth and progress as a pediatric neurosurgeon. I have not been let down.”

Naftel’s specialty focus areas include epilepsy surgery, hydrocephalus treatment, spasticity surgery and endonasal (through the nose) surgery. He continues to look for medical advances in treating hydrocephalus (fluid accumulation on the brain) and traveled to Africa to learn from world experts.

“My favorite thing about our work is seeing my patients and their families back in clinic after we have treated them—especially when they have been through a really challenging medical problem,” Naftel said. “When I first meet them, there is understandably a lot of stress surrounding their neurosurgical diagnosis. In contrast, when I see them after surgery, we have a very different type of relationship. We have all been through something major together. The stress is gone and instead there is often laughter.”

Outside the office Naftel and his wife, Kimberly, spend time chasing after their toddler daughter and pet Goldendoodle. He enjoys running, and he and his wife also like to ski as well as bike both locally and as far away as Paris and Italy.

– by Tavia Smith

 

As a stem cell transplant physician Carrie Kitko, M.D., is keenly aware of the fine line she walks between cure and complication.

While her goal is to cure children with challenging cancers and other conditions such as immune deficiencies and sickle cell disease, patients sometimes develop a very significant complication after the transplant called graft-versus-host disease (GVHD).

“The transplanted bone marrow generates a new immune system that unfortunately sometimes goes rogue and attacks the patient, or ‘host,’” said Kitko, associate professor of Pediatrics and medical director of the Pediatric Stem Cell Transplantation Program. “So for some of my patients, I feel like I cure one disease, but give them something that can be just as bad.

“I really want to gain a better understanding of who gets this complication and try to predict who’s going to get it, which may allow me to start treatment sooner or more aggressively,” she said.

Her aim is to “try and learn from each and every patient, and make treatment better for those that come next.”

At the University of Michigan, first as a fellow and then as a faculty member, Kitko worked with a team of investigators to discover biomarkers for acute GVHD, which typically develops in the first 100 days after transplant. This was done using blood samples collected from patients at various timepoints after transplant.

The team developed an algorithm based on three biomarkers to calculate a risk score—the Ann Arbor GVHD score—that predicts which patients are at the highest risk of dying from acute GVHD. Kitko is leading Vanderbilt’s participation in two national studies using the biomarker panel at the onset of GVHD to help determine treatment. She is also helping develop a pre-emptive treatment trial for patients with high-risk biomarkers detected only seven days after their transplant, with the goal of preventing GVHD altogether.

In addition, Kitko is leading a multi-center study of extracorporeal photopheresis as a treatment for pediatric acute GVHD. Photopheresis uses a machine to separate and collect a patient’s white blood cells, which are then treated with a medicine that is activated by ultraviolet light and infused back into the patient. The treatment “calms” the immune system and improves GVHD.

Kitko and her University of Michigan colleagues also discovered a biomarker that is present at the onset of chronic GVHD—a form of GVHD that develops later after transplant and can affect almost any part of the body. Kitko is particularly interested in this form of GVHD, which can impact a patient’s quality of life for years.

“I think by the time I can look at a patient and say, ‘you definitely have chronic GVHD,’ the disease has been burning just under the surface, evading detection, for a while. If we can find biomarkers to help predict this complication, I could start treatment much earlier,” said Kitko. “Finding the right way to catch it early is essential and will take a coordinated effort between centers that follow their patients long term.”

Recognizing the importance of team science, Kitko is forming a pediatric chronic GVHD consortium of centers to follow patients and build a biorepository for additional biomarker discovery.

Kitko knew from a young age that she wanted to be a physician, and by high school she had decided to pursue a career in pediatrics. Following her pediatrics residency at Duke University, she completed a Hematology/Oncology fellowship.

Kitko joined the faculty at Vanderbilt in summer 2015, after 12 years at the University of Michigan. She and her husband, a nephrologist, stay busy with their 10-year-old son and his sports activities, and they enjoy collecting wines from around the world to share with friends and family.

– by Leigh MacMillan

 

 

Atia K. Jordan, M.D., wanted to be a doctor and help sick children before she knew the word pediatrician.

The assistant professor of Clinical Pediatrics followed her dreams and accomplished her goals all at Vanderbilt University, a place she calls home.

“I have wanted to be a doctor since I was a little girl,” Jordan said. “To this day, my mom tells people that (as a child) I walked around telling people I wanted to be a children’s doctor—and it never wavered. I’ve always loved working with children and felt it was a good fit for me.”

The Collierville, Tennessee, native had a big choice after graduating high school: where to attend college and pursue her medical degree.

“I initially thought I wanted to go to college far from home. I came to visit Vanderbilt and was immediately impressed by the people I met and the campus itself. I knew this is where I wanted to be,” Jordan said. “With each phase of my education and training, I have found it difficult to leave Vanderbilt. From undergraduate, to medical school, fellowship, and now as an attending physician, Vanderbilt has continued to be the place where I can grow as a person and physician, as well as progress in my career.”

After obtaining her Bachelor of Science degree in 2005, and her medical degree in 2009, Jordan completed an internship and residency at Cincinnati Children’s Hospital. She returned to her alma mater to complete a fellowship in sleep medicine.

While a sleep-deprived resident doing a pulmonary care rotation, she noticed frequent discussions about sleep, but did not feel she had the tools to adequately educate her patients and families.

“Between my medical interest and desire to provide more advice and education for my patients, I pursued sleep medicine further,” Jordan said.

In 2014, she became an attending physician at Monroe Carell Jr. Children’s Hospital at Vanderbilt. Jordan is a general pediatrician who focuses on pediatric sleep medicine and cares for children with various sleep disorders, including obstructive sleep apnea, insomnia and narcolepsy/excessive daytime sleepiness.

“Sleep is so important to the overall health and well-being of everyone, especially in children as they grow, develop, learn and experience the world around them,” Jordan said. “When the kids sleep well, parents are happy. Kids are happy. I’m happy. It makes me feel like I have helped not just the child, but the entire household. The children are typically doing well in school, becoming more active, expanding their friend groups and thriving. That is what is most important to the families and myself.”

Jordan enjoys spending time with her parents, younger brother, closest friends and extended family. She also loves to travel around the world.

“There is so much world (and even country) to see, and I get away as often as I can. I have even taken a few solo trips, which have been awesome experiences,” Jordan said.

She also loves to craft and exercise her artistic skills. Spending an afternoon roaming around a craft store and working on five to six craft projects brings her solace and peace.

“I am actually a pretty shy and reserved person. I would consider myself an introvert,” Jordan said. “My patients ask how I do a job where I talk to people all day. I always respond, ‘I’m not really sure.’ But I suspect it has to do with my patients and the medical students I work with who motivate me to be better and do better on a daily basis.”

– by Tavia D. Smith

 

 

Timothy Eidson, M.D., is the definition of a community pediatrician. His practice, Rivergate Pediatrics, is about a mile from Gateway Elementary School, where he went to school. Some of his patients are students there now.

Eidson grew up in Goodlettsville, Tennessee, and only left long enough to attain his college degrees and complete his residency at Baylor College of Medicine in Houston, Texas.

He returned 16 years ago to join the staff at Rivergate Pediatrics, where he and four other pediatricians serve the community. Goodlettsville is also his home, where he lives with his wife, Stephanie Eidson, M.D., and children, Matt, Elizabeth, Mariana and Mark.

Eidson, associate clinical professor of Pediatrics, has long ties to Vanderbilt. He hosts one or two students from the School of Medicine at his office each year. Those students voted to give him the Alpha Omega Alpha Clinical Faculty Award for 2012.

For more than a decade, he has served on the Physician Advisory Council at Monroe Carell Jr. Children’s Hospital at Vanderbilt. At least four times a year, he shares information with top hospital leadership.

“That relationship has been very good and I’m happy that Vanderbilt sees the importance of involving the community in changes or decisions that are made at the Medical Center,” he said.

Stephanie Eidson, his wife, is also part of the Vanderbilt family. She is an assistant professor of Clinical Pediatrics and works at the Vanderbilt Children’s After-Hours Clinic in nearby Hendersonville, Tennessee. The couple met at Baylor, where both of them completed their residency.

“I love being part of Vanderbilt,” Timothy Eidson said. “The specialists have been there for me and my family, and for my patients. I trust the specialists there to take care of my patients like I would want them to be taken care of. I have relationships that we have fostered over 15 years, that mean something, that allow me to take care of my patients better because I know the physicians. I know the nurses.”

When Eidson isn’t running a successful practice, he’s running on the pavement. He’s completed more than 10 half-marathons and one marathon. “My kids are starting to enjoy running, and so we enjoy some of that together,” he said. He plays piano, as do each of his children, who range in age from 8 to 13.

Eidson, an elder and Sunday school teacher at Sumner County Upper Cumberland Presbyterian Church, said community work is important to him. He and his wife teach prenatal classes at the Cumberland Crisis Pregnancy Center in Gallatin.

“And we do it together, so it’s really fun because we’re different personalities,” he said. “We kind of play off each other a little bit.”

He’s also the former president of the Cumberland Pediatric Foundation, where he’s passionate about public health. One of his recent initiatives was promoting the HPV vaccine to prevent cancer. The Tennessee Chapter of the American Academy of Pediatrics awarded him Pediatrician of the Year in 2014 for his work in the community and with the Cumberland Pediatric Foundation.

Community outreach is something that’s important to all the physicians at Rivergate Pediatrics.

“(The practice) has been here nearly four decades,” he said. “We are all very active in various areas outside of Vanderbilt.”

– by Matt Batcheldor